Title: Full Professor
E-mail: [email protected]
Lattes: http://lattes.cnpq.br/1810614032141202
Bolsa produtividade CNPq: PQ 1A
Orcid: ID 0000-0002-0520-4681 – https://orcid.org/0000-0002-0520-4681
Scopus: ID 7004486222 – https://www.scopus.com/authid/detail.uri?authorId=7004486222
Google scholar: ID wGAjdvkAAAAJ – https://scholar.google.com.br/citations?user=wGAjdvkAAAAJ&hl=pt-BR&oi=ao
Research ID: B-8438-2012 – https://publons.com/researcher/1495907/eloisa-bonfa/
Line of Research
Autoimmune Rheumatological Diseases, with emphasis on Systemic Erythematosus Lupus, Autoantibodies in Autoimmune Diseases and Biologic Therapy in Autoimmune Rheumatological Diseases.
Summary
The main lines of research are the clinical, laboratorial and immunological aspects of autoimmune rheumatological diseases, especially systemic erythematosus lupus. I have made relevant contributions to the field of autoantibodies, with special focus on the description and characterization of antiribosomal P antibodies and their association with the psychiatric manifestations of lupus. Also of note is the first identification of the arrhythmogenic potential of Ro/SSA antibodies purified in vitro. Recently, we initiated studies on immunogenicity and the safety of vaccines in autoimmune diseases, which resulted in several publications. Currently, I am studying and evaluating biologic therapy in autoimmune rheumatological diseases and have published several articles on this topic.
Main Publications
- Bonfa E, Golombek SJ, Kaufman LD, Skelly S, Weissbach H, Brot N, Elkon KB. Association between lupus psychosis and anti-ribosomal P protein antibodies. N Engl J Med. 1987;317(5):265-71. doi: 10.1056/NEJM198707303170503.
- Borba EF, Bonfá E. Dyslipoproteinemias in systemic lupus erythematosus: influence of disease, activity, and anticardiolipin antibodies. Lupus. 1997; 6(6):533-9. doi: 10.1177/096120339700600610.
- Pons-Estel BA, Catoggio LJ, Cardiel MH, Soriano ER, Gentiletti S, Villa AR, Abadi I, Caeiro F, Alvarellos A, Alarcón-Segovia D; Grupo Latinoamericano de Estudio del Lupus. The GLADEL multinational Latin American prospective inception cohort of 1,214 patients with systemic lupus erythematosus: ethnic and disease heterogeneity among “Hispanics”. Medicine (Baltimore). 2004;83(1):1-17. doi: 10.1097/01.md.0000104742.42401.e2.
- Saad CG, Borba EF, Aikawa NE, Silva CA, Pereira RM, Calich AL, Moraes JC, Ribeiro AC, Viana VS, Pasoto SG, Carvalho JF, França IL, Guedes LK, Shinjo SK, Sampaio-Barros PD, Caleiro MT, Goncalves CR, Fuller R, Levy-Neto M, Timenetsky Mdo C, Precioso AR, Bonfa E. Immunogenicity and safety of the 2009 non- adjuvanted influenza A/H1N1 vaccine in a large cohort of autoimmune rheumatic diseases. Ann Rheum Dis. 2011;70(6):1068-73. doi: 10.1136/ard.2011.150250.
- Ugolini-Lopes MR, Seguro LPC, Castro MXF, Daffre D, Lopes AC, Borba EF, Bonfá E. Early proteinuria response: a valid real-life situation predictor of long-term lupus renal outcome in an ethnically diverse group with severe biopsy-proven nephritis? Lupus Sci Med. 2017;4(1):e000213. doi: 10.1136/lupus-2017-000213.