The program has a ROBUST INSTITUTIONAL INFRASTRUCTURE with emphasis on state-of-the-art laboratories.

We have access to the University of São Paulo infrastructure park and, mainly, to the Hospital das Clínicas Complex of the USP Medical School. The HC Complex occupies a total area of 600,000 square meters with around 2,400 beds distributed among 8 specialized institutions and 2 auxiliary hospitals.

The University of São Paulo Medical School (FMUSP) is recognized for its pioneering spirit and excellence in teaching, research and university extension environments. The institution invests in modernization, technological innovation and its educational platform, in addition to building partnerships with the private sector and expanding the internationalization process to be an educational center of reference in the world. The USP Medical School is made up of 17 departments, among them the Department of Orthopedics and Traumatology and the Department of Clinical Medicine, to which belong the disciplines of Rheumatology, General Practice and Propaedeutics, Clinical Emergencies, Endocrinology and Metabology, Geriatrics, Hematology and Hemotherapy, Clinical Immunology and Allergy, Molecular Medicine and Nephrology.

For research project development, we have the building of the FMUSP Institute of Orthopedics and Traumatology (IOT) at the disposal of our Program students, which brings together all the teaching, research and care activities of the Department of Orthopedics and the entire Rheumatology area, which has laboratories in the main FMUSP Building and also areas within the Hospital das Clínicas itself.

The IOT occupies two buildings, the first with ten floors and the second with four, totaling 25,000m² of building space. Both are dedicated to the treatment of diseases of the locomotor apparatus. The IOT also has seven specialty laboratories and a clinical staff of approximately 160 doctors, among them orthopedists, residents in the specialties and a team of anesthesiologists. Other members of the group include pediatricians, geriatricians, physiatrists, chest and plastic surgeons, urologists and cardiologists, who provide medical support to orthopedic patients. It has laboratories equipped to meet the needs of the teachers, students and researchers and a Surgical Center with 11 rooms, also considered as a place for teaching and the development of various research projects. Within the structure, a Clinical Research Center was designed and conceived according to rigid Good Clinical Research Practices standards. The Physical Medicine Division (625 m2 of rehabilitation infrastructure) is noteworthy, including Physiodiagnostic Services, the Rehabilitation Service and the Physical Therapy Service. There is an Occupational Therapy Service, a Psychology Service and a Medical Social Service. There is also a specific Prostheses and Orthoses division (760m2 of workshops), made up of the Surgical Instrumental Production Service – Prostheses Unit, Orthoses Unit, the Saddle, Vest and Shoe Unit, in addition to the Administrative Unit, storage and support areas. The IOT has a Radiology Center with magnetic resonance, radiography and ultrasound apparatus and a report room devoted to the Musculoskeletal System that facilitates graduate student access to practical learning, as well as the use of these methods in research projects.

In Rheumatology, we have a research area inside the medical school where the LIM 17 is located (Rheumatology Investigation Laboratory), which has eight laboratories, all renovated with help from FAPESP, and that offer training in basic and clinical research in Cellular Immunology, Humoral Immunology, Extracellular Matrix, Bone Metabolism, HR-pQCT, Bone Densitometry & Bone Biopsy, Lyme (Baggio Yoshinari Syndrome), Inflammatory Myopathies, Applied Physiology & Nutrition and Antiphospholipid Syndrome. We also have a Vivarium for experimentation in the Clinical Medicine Department that is coordinated by the Rheumatology discipline. The Rheumatology ward, located in the Central Institute of the Hospital das Clínicas, has 16 hospital beds distributed in double rooms and 10 beds for the Rheumatology day-hospital. Our group handles approximately 29,000 patients per year in 24 specialized walk-in clinics, screening, requests for consultation and infiltration. All assistance is carried out using electronic medical records, in a pioneer program using a specialty-specific database. It also has training areas in ultrasound, capillaroscopy, sports medicine applied to rheumatological diseases, infusion center and research experience. Another part of our Service is a Physical Conditioning and Rehabilitation Laboratory for Rheumatological Patients (LACRE) and a Multidisciplinary Center for Dispensing High-Cost Medications (CEDMAC). The latter is in a partnership with the São Paulo State Secretariat and has become the Coordinating Center for a central biologics network associated with tertiary hospitals in the State of São Paulo.

LABORATORIES:

MUSCULOSKELETAL SYSTEM MEDICAL INVESTIGATION LABORATORY

Previously tied mainly to resistance tests and animal research, it incorporated the activities of several laboratories, such as movement studies, pathological anatomy, locomotor apparatus biomechanics, microsurgery, arthroscopy, tissue bank, clinical research center, spinal cord trauma, vivarium etc. The laboratories have specialized technical staff to collaborate in the research.

MOVEMENT STUDIES LABORATORY (LEM)

LEM is a center of excellence in research in the area of functional assessment. In 2010, together with the Sports Medicine Group, it was certified by FIFA as a Medical Center of Excellence. Its structure allows it to perform all the evaluations related to exercise physiology in a single location. At LEM, works of scientific initiation are conducted: undergraduate courses, regular research projects and projects in the stricto sensu graduate studies area.

We highlight the following equipment belonging to the laboratory:

  • Cybex 6000 Testing & Rehabilitation System Isokinetic Dynamometer
  • Biodex Medical System 3 Pro 830-206 Isokinetic Dynamometer
  • MedGraphics CPX/D System Spirometry System
  • HeartWare version Ergo 13 Ergometry System
  • Tekscan F-Scan version V.5.72 Podobarometry System
  • Balance Master Biodex NeuroCom Balance Master System
  • 2 AMTI OR6-7-2000 Force platforms
  • AMTI ACS-Plus-BC-BT Mobile Force platform
  • BioSpace Co. In Body R230 Fat Percentage Analyzer
  • 6 treadmills (various brands/models)
  • 8 Cybex The Bike stationary bicycles
  • Weight training equipment (different types/makes/models)
  • GMBH Foerster Standard steering simulator
  • Ecomed Swissdolorclast shock wave therapy equipment

ANATOMICAL PATHOLOGY LABORATORY

It is a center of reference in the area of Bone Pathology, especially in musculoskeletal tumors, and is a mandatory internship for residents in Pathological Anatomy at the USP Medical School and at IOT itself. It develops research in the areas of joint cartilage pathology, spinal cord injury and musculoskeletal tumors.

The existence of equipment that allows the execution of histological cuts of the areas of integration between implants and bone is noteworthy, as it significantly expands the research possibilities in this area. We highlight the following equipment:

  • Incomar band saw (macroscopy room)
  • International Equip. Company IEC – CTD Microtome Cryostat (macroscopy room)
  • Oma DM-80 histotechnical apparatus (technical processing room)
  • 2 Leica RM 2165 and American Optical 820 microtomes for histological sections (technical processing room)
  • Zeiss Axioskop 2 Plus photomicroscope (microscopy room)
  • Zeiss Standard 25 optical microscopes (microscopy room)
  • 3 scientific laminar flow cabinets (microscopy and technical processing rooms)

LOCOMOTOR APPARATUS BIOMECHANICS LABORATORY

Its main line is the development of research that involves mechanical analyses of locomotor apparatus structures and simulations of surgical reconstructions. In this laboratory, projects focused on equipment, quality control, and performance of the biomechanical products used at the Institute are conducted. The Prostheses and Orthoses Division, an orthopedic workshop that fabricates special devices and prototypes of equipment under development, integrates and interacts with the Biomechanics Laboratory. It also works with the fabrication and maintenance of surgical instruments and implant materials of different types and applications. This laboratory includes an area for the storage and preservation of anatomical parts and of the preparation of specimens, an area for mechanical tests and trials and biomechanical simulations, stress analysis and metrology, and a biological studies area (with a hygiene and dressing room, quarantine, experimental surgery center, maintenance vivarium and support areas).

We highlight the following equipment that belongs to the laboratory:

Bioengineering Area:

  • Kratos K5002 universal mechanical test machine
  • Lynx ADS 2000 digital data acquisition system
  • Claron Microntracker three-dimensional optical navigation system
  • Durometer, model Panambra Pantec RBS
  • Micro-Measurement model P-3500 electric extensometry equipment (strain gage)
  • Micro-Measurement MOD 031-A photoelasticimetry equipment
  • Deltronic DV 114 profile projector
  • Mitutoyo 178-934 rugosimeter
  • Micronal model SIT SZ metallographic microscope
  • ASTM D-638 standard press for specimen preparation
  • Metalac MTE-100 digital torque wrench
  • Mitutoyo pachymeters, micrometers and other metrology instruments
  • Acculab V-1200 1.2kg electronic scale
  • Robertshaw LDT 900 digital thermometer
  • Nova Técnica NT – 245 microprocessor-controlled water bath
  • 20 MHz ICEL SC-6020 two-channel oscilloscope
  • ICEL LD 500 digital luxmeter
  • PIC (Microchip) Labtools ICD2 microcontroller recorder and debugger

Biological Research Area:

  • Experimental surgery center with laminar flow
  • Climate-controlled maintenance vivarium for animals (36 simultaneous animals)
  • Laboratory animal receiving room (quarantine)
  • Takaoka 2604 anesthesia device with ventilator
  • HP 78339A ECG, pressure, temperature and O2 saturation monitor
  • Baumer Centr-450 surgical light
  • CG-1 CEC electrocoagulator
  • Dri-Tec Statim 5000 autoclave
  • Webeco A12/30 autoclave
  • Fisatom water distiller
  • Arsec 200M3U dehumidifier
  • Balmak MP10 10kg electronic scale
  • Fento 432C spectrophotometer
  • Celm DA 500 diluter
  • Hanna Instruments HI 8314 portable pH meter
  • Drucker refractometer
  • New Japan NJ 300 industrial vacuum cleaner

RECONSTRUCTIVE MICROSURGERY LABORATORY

It works to train doctors in the area of reconstructive microsurgery, in addition to conducting research in reconstructive surgery of peripheral nerves and the spinal cord, with a significant contribution to the scientific advancement of the area. It has constant monitoring and an extensive training program (4 months) and an intensive one-week program, according to the availability of the interested party. The Reconstructive Microsurgery and Hand Surgery Emergency Care Center assists patients who are victims of trauma resulting in type III-B and III-C Gustilo and Anderson exposed fractures, traumatic limb amputations, peripheral nerve injuries and complex traumas of the hand, amputated limb replantations, emergency microsurgical flaps, emergency peripheral nerve reconstruction, treatment of complex hand injuries (osteosyntheses, repairs of tendon injuries, reconstructive surgeries). In 2018, it received funding from the Itaú Social Foundation to readapt the microsurgery room belonging to the Microsurgery Laboratory of the IOT/HC/FMUSP (see specific fundraising item).

The structure enables the simultaneous training of several graduate students, as well as the execution of complex microsurgery research projects. The laboratory is equipped with 5 DF Vasconcelos MC-A184 surgical microscopes, 3 workbenches, 2 Emai BO-50 microcoagulators, 2 ASSI surgical microinstrument toolboxes, 5 AESCULAP surgical microinstrument toolboxes, Stermax autoclave, Odontobrás EL material drying oven, television and image recording systems.

In 2018, the laboratory received R$200,000.00 from the Itaú Social Foundation to readapt the microsurgery room belonging to the Microsurgery Laboratory of the IOT/HC/FMUSP.

The Rotary Microsurgery Laboratory of the Institute of Orthopedics and Traumatology (IOT), founded in 1997, was reopened on October 11, 2019. It is larger and equipped with twelve state-of-the-art microscopes for training that ranges from suturing in gloves to the technique of microanastomoses in small-caliber blood vessels. The laboratory is resuming its activities after a 4-month renovation. The structural redesign to better accommodate and teach courses was made possible through a partnership with the IOT, the Rotary Club and Banco Itaú. “The excellence of the Microsurgery Laboratory is proof of the importance of partnerships with the private sector, combining university expertise with private sector resources.”

ARTHROSCOPY LABORATORY

This is the first Arthroscopic Surgery learning and training laboratory for the shoulder, hip and knee installed in Brazil. The training programs offer learning, improvement and development of specific skills and new techniques, in addition to experimentation with new materials, and is highly sought after by doctors from all over the country.

REGENERATIVE ORTHOPEDICS, TISSUE BANK AND CELLULAR THERAPY NUCLEUS

The Regenerative Orthopedics, Tissue Bank and Cellular Therapy Nucleus was established in 2018 following a cutting-edge trend in the development of this type of research line. Important centers in the USA and Europe initiated this research and development center model. Currently, the frank and exponential development in the area of musculoskeletal system regenerative medicine stands out. In the cellular therapy sphere, new Brazilian regulations/legislation were published in 2018, demonstrating the timeliness of the topic.

The establishment and development of the research Biobank/Biorepository in this area is intended. With the existence of this center, it will be possible to expand the research lines involving Cellular Therapy and Regenerative Orthopedics. The Nucleus comprises the Tissue Bank that has existed since 1952 and today it has the most modern technologies to meet the standards of ANVISA and the National Transplant System. Its basic goal is the procurement and processing of bone tissue, cartilage, tendons, fascia and ligaments. It has its own processing and cryopreservation unit, and an autonomous Surgical Center.

CLINICAL RESEARCH CENTER

The center is dedicated to conducting research with medications and special materials that are still under investigation for clinical effectiveness, tolerance and safety, strictly within the international standards for clinical research.

SPINAL CORD AND NERVE TRAUMA STUDY LABORATORY– LETRAN

This was created for the execution of interinstitutional research, supporting and integrating the laboratories and researchers from state centers of reference and the other participating institutions. It implemented and standardized an experimental model for Spinal Injury in Wistar Rats, using computerized equipment for drop weight impact testing (New York Impactor – computerized drop weight impact equipment for producing controlled spinal cord lesions, developed by New York University – USA).

MICROORGANISM AND ARTHRITIS LABORATORY

The Microorganism and Arthritis Interaction Laboratory studies an infectious disease transmitted by the bite of ticks called Lyme-like Disease or Baggio-Yoshinari Syndrome. This disease has skin, joint, neurological and cardiac involvement. The disease is diagnosed considering the clinical manifestations, the epidemiology and serological analysis against the etiological agent of the disease. Thus, the laboratory developed and standardized immunological assays for the detection of IgG- and IgM-class immunoglobulins and currently conducts ELISA (Enzyme Linked Immunosorbent Assay) and Western Blotting for the entire HCFMUSP complex, as well as for university hospitals, institutes and central laboratories throughout Brazil. The Microorganism and Arthritis Interaction Laboratory develops research in the area of Molecular Biology in order to identify species of bacteria (Borrelia sp) involved in the etiology of the disease in biological material from humans, domestic and wild animals, and ticks with the collaboration of veterinarians and biologists. Bacteriological and biotechnical research is currently underway in collaboration with Butantan Institute, the main goal of which is to improve laboratory diagnosis of the disease to assist clinical practice. This project is called “Improvement of the serological testing and physiological characterization of the Baggio-Yoshinari Syndrome (Lyme-like disease) as a way to assist diagnosis” and has robust funding from FAPESP. The laboratory makes equipment, supplies and knowledge in the areas of microbiology, immunology and molecular biology available to undergraduate and graduate students.

RHEUMATOLOGY EVALUATION AND CONDITIONING LABORATORY (LACRE)

The objective of LACRE is to study the effects of programmed physical exercise (physical training) on patients with different rheumatological pathologies. In addition to this research, the laboratory also serves a didactic purpose, as the team gives classes on the locomotor apparatus and physical activity, and also trains residents and graduate students to prescribe physical conditioning to rheumatology patients.

The laboratory has weight training equipment, treadmills and devices for conducting ergospirometric and physical function tests. The laboratory also has accelerometers and frequencimeters that permit assessment of the level of physical activity in patients. Blood collection is done in partnership with the Central Laboratory. LACRE also has a room dedicated especially to invasive procedures (blood collection and muscle biopsy), which allow investigation of the mechanisms associated with acute and chronic adaptations to exercise. While the central focus of LACRE is the study of rheumatological diseases, the laboratory also contributes to projects in other disciplines, such as Neurology.

A variety of projects are developed in the laboratory, not only with patients from Rheumatology, but also from associated clinics, such as Bariatric Surgery, Gastroenterology, Endocrinology, Pediatrics, Urology, Nephrology and Cardiology.

LACRE hosts the main activities of the Applied Physiology & Nutrition Group, whose mission is to conduct comprehensive clinical or experimental studies with the aim of discovering the role of physical activity and nutrition in sports, aging, obesity and in chronic illnesses. The group works transdisciplinarily, consisting of Scientific Initiation, master’s, doctoral students and postdoctoral researchers, with a wide variety of basic backgrounds, including Physical Education, Sports, Nutrition, Physical Therapy, Medicine, Biology, Pharmacy and Mathematics. The research laboratories occupied by the group are located at the Medical School (LIM-17), in the Hospital das Clínicas (LACRE) and the USP School of Physical Education and Sports. Together these laboratories offer ample possibility for the physiological evaluation and testing of patients and athletes, as well as prescribing exercise programs. Molecular analyses of gene and protein expression, enzymatic assays, high performance liquid chromatography, histology and cytology are techniques performed by the group, which also has a “fish pole” scale, developed in partnership with the USP Polytechnical School, and that allows the measurement of isolated fibers, an essential step in cellular physiology investigations. The group also collaborates actively with several researchers from the program and others from the Institution.

CELLULAR IMMUNOLOGY LABORATORY

The Cellular Immunology Laboratory analyses and evaluates immunoregulatory changes involved in immune system cells, in peripheral mononuclear cells in particular. The study focus is on rheumatological diseases in humans and in experimental models of systemic lupus erythematosus and scleroderma. The methodology used involves induction of the disease in the animal model and analyses of cellular function, membrane receptor expression, secretion of cytokines and apoptosis, using culture techniques, cell marking and flow cytometry.

HUMORAL IMMUNOLOGY LABORATORY

The Humoral Immunology Laboratory (LIH) conducts research on the humoral immunological factors in autoimmune diseases of the connective tissue, which includes the characterization of the panel of circulating antibodies relevant to the diagnostic support and monitoring of the clinical activity of rheumatological diseases, the exploration of their potential clinical association, as well as the definition of serum complement and cytokine levels.

Currently, the main function of the LIH is to contribute to research, since most of the diagnostic routine was transferred to the Central Laboratory Division (DLC) of the HCFMUSP when the Autoimmunity Diagnostics Laboratory (LDA) was created (partnership between the DLC and the LIM17).

This partnership between the LIH and the DLC also focuses on teaching and research. The teaching includes theoretical and practical classes on detection methods and the clinical applicability of autoantibodies given by Dr. Sandra Gofinet Pasoto to undergraduate medical students at FMUSP, Clinical Pathology and Rheumatology residents and recent graduates in Biomedicine at DLC. In addition, teaching material consisting of several chapters from A Treatise on Clinical Pathology, edited by Prof. Alberto Duarte is being prepared.

Scientific Initiation students Paola Giulia Conde, Raony Ferreira França and Tamires Feliciano Floriano, and technical training student Nicole Andressa Gomes Fontoura are joining the team at the LIH.

BONE METABOLISM, HR-pQCT, BONE DENSITOMETRY AND BONE BIOPSY LABORATORY

The Bone Metabolism Laboratory provides infrastructure for studies related to bone metabolism through the analysis of bone mineral density and bone microarchitecture parameters. These analyses are possible through image acquisition using the bone densitometry equipment installed in our laboratory unit (HOLOGIC-Discovery model and GE–iDXA model, acquired through funding from FAPESP and FINEP, respectively). Additionally, the equipment is able to perform body composition analysis through full-body image capture, often used in longitudinal studies evaluating obese individuals undergoing bariatric surgery, as well as in studies evaluating muscle mass and fat mass in patients participating in physical exercise.

The bone densitometry equipment has software to evaluate vertebral fracture, bone mass in children, and software able to evaluate bone microarchitecture by assessing the trabecular bone score (TBS).

The laboratory unit also has high resolution peripheral quantitative computed tomography equipment (HR-pQCT), acquired through FAPESP financing, that allows non-invasive three-dimensional evaluation of density and bone structure parameters. More recently, also through funding from FAPESP, the unit has implemented high-resolution equipment for bone histomorphometry analysis from bone biopsy, with infrastructure for the processing of bone fragments to final analysis.

These methodologies are widely used by medical and non-medical graduate students in the areas of rheumatology, cardiology, nephrology, gastroenterology, physical education, endocrinology in working collaboratively. In addition to the imaging area, the laboratory has infrastructure for studies in the area of cellular biology using a methodology developed for the culture of osteoclasts and osteoblasts, and for studies associated with molecular biology and genetics with a structure for performing RNA and DNA extraction, PCR and sequencing.

INFLAMMATORY MYOPATHIES LABORATORY

The main objective of this laboratory is to integrate clinical and basic scientific knowledge, from bench to bedside, in the area of systemic autoimmune myopathies, which include dermatomyositis, polymyositis, immune-mediated necrotizing myopathy, antisynthetase syndrome, among others.

ANTIPHOSPHOLIPID SYNDROME LABORATORY

The objective of the Translational Research Laboratory for Antiphospholipid Syndrome is to study clinical and laboratorial factors that allow a better understanding of the pathogenesis of this disease in a manner applicable to clinical medicine. To do this, we have sought a multidisciplinary approach. Antiphospholipid Syndrome is an uncommon/rare disease described in the 1980s with a fundamental need for research in order to find answers to the numerous uncertainties related to the disease.

EXTRACELLULAR MATRIX LABORATORY

The line of research of the laboratory is “Tissue and molecular aspects of the structure and function of extracellular matrix proteins in inflammatory and fibrotic processes”, and its objective is to investigate the tissue and molecular aspects of the structure and function of extracellular matrix proteins with emphasis on the different isoforms of collagen. It is known that collagen, in addition to being responsible for tissue structure, performs functions of cell adhesion, proliferation and migration and that together with the glycoproteins of the cell membrane can promote cellular signaling and immunogenicity. Uncontrolled gene expression synthesis from post-transcriptional changes or changes in essential transcription factors leads to defects in the differentiation and proliferation of cells that culminate in the activation of inflammatory and fibrotic processes present in degenerative autoimmune and osteoarticular diseases. The proposal of the laboratory is to evaluate the inflammatory and osteoarticular process control mechanisms that culminate in the activation of the inflammatory process and cell proliferation and differentiation “in vitro” and “in vivo” in animals and humans, focusing on the applicability of the knowledge generated to future therapeutic and diagnostic tools.

NUCEL and MedCell

It should be noted that the administrative philosophy and regulatory structure of the University of São Paulo Medical School facilitate student and researcher access to other Institution laboratories and equipment parks. Regarding the lines of research of this Program, the recent development of cell therapy laboratories is highlighted. These laboratories, which aim to bring basic research closer to clinical application, are currently seeking ANVISA authorizations to operate in line with the norms of RDC 260 of 12/21/2018 and RDC 214, which address good practices for the use of human cells for therapeutic and clinical research purposes. NUCEL and MedCell were conceived along this line. MedCell, the HC-FMUSP Cellular and Regenerative Medicine Center, consists of a strategically built area, attached to the Surgical Center to enable and facilitate the transit of donor organs, tissues and cells to recipients under sterile conditions. This area was designed to allow the isolation, cultivation and manipulation of cells to be used in clinical cell therapy and tissue engineering protocols throughout the Institution. The Cellular and Molecular Therapy Nucleus (NUCEL – www.usp.br/nucel) was created in April 2012, through an Ordinance of the Rectory of the University of São Paulo (GR3.337), as a Research Support Nucleus (NAP) that brings together faculty from different USP departments with similar lines of research. The Translational Research Center, CTC-NUCEL, a product of the Nucleus, which became part of the USP Medical School in December 2012, occupies three floors of 500m2 each, a 500m2 technical floor and a 250m2 service area containing separate enclosures for the two transformers and the generator that supply around 75% of the building, and a 2,500L water tank. The Center has 3 laboratories for cell processing (with areas of 26m2, 21.4m2 and 21.4m2) and a laboratory for processing genetically modified cells (26.7m2 in area). We believe that the Center will encourage projects related to cell therapy in the musculoskeletal system with greater interaction among different knowledge areas (for example, bioengineering). In the scientific interface areas it will be possible to conduct pioneering and cutting-edge projects, allowing us to expand the scope and the academic-scientific impact of our Program.

INFORMATION TECHNOLOGY

The Program has competent IT professionals to support the teaching and research area by opening a call via the Intranet. All the auditoriums and departments are equipped with computers with internet access, video projectors, and a complete infrastructure for the development of teaching and research at the Institution. We have a professional to film and edit video of surgeries, classes and clinical meetings, which are posted on the iothcfmusp and e-Ortopedia websites. We have a teleconferencing room that can transmit classes and lectures.

The Medical School has amphitheaters, auditoriums and rooms supported by IT professionals, all with internet access and webconferencing support. Students can reserve rooms as needed and use them for internet and intranet access, in addition to being able to connect their own equipment for display on the TV available in each room, assisting the development and training of qualification classes and thesis and dissertation defenses. Students have access to the FMUSP library, where computers with internet access and an extensive collection of online periodicals are available.

The Medical School has the LabHab, the FMUSP Skills and Simulation Laboratory, opened in 2006. There are 6 modular spaces equipped for professional training, from simple skills to complex simulations, which hold up to 30 students simultaneously and support the curriculum activities of undergraduate courses in Medicine, Physical Therapy, Speech Therapy and Occupational Therapy, and also the residency programs at the Hospital das Clínicas, extension and graduate courses. LabHab has advanced national and imported technology and low complexity equipment that support skills learning in diverse areas of health. LabHab has a trained team of employees to assist in setting up teaching scenarios.

LIBRARY

The goal of the Professor Manlio Mario Marco Napoli Library Scientific and Academic Documentation Service (SBDCD) of the Institute of Orthopedics and Traumatology is to support the teaching and research activities of the medical, paramedical and graduate communities of the institution, by means of the treatment, recovery and dissemination of area information. The service is organized into Library, Scientific Documentation, and Academic and Institutional Activity Support sections. It is the most complete library in the area of Orthopedics and Traumatology in all of South America. Created in 1953, its historical collection of books and periodicals is considered a reference for all teaching institutions in Brazil.

The Library has a collection of approximately 2,200 books, 369 master’s dissertations, 368 doctoral theses, 85 monographs, 108 memorials, 93 course syllabuses, 136 periodical titles, 384 CD-ROMs and 301 DVDs, as well as a collection of 23,000 slides. It also has access to the SIBI, CAPES, PUBMED, BIREME, and ISI databases, among others in the health field for retrieving the full text of articles and conducting bibliographical reviews.

The SBDCD has both its own resources and those of the Godoy Moreira Study Center – CEGOM and seeks to procure funding from official finance agencies and, mainly, from private sector donations.

The Scientific and Didactic Documentation Center provides the didactic support necessary for presentations of scientific works through the creation of images, videos and classes with multimedia resources, as well as clinical meetings and Teleorthopedics.

Services Provided: Searches for articles in national and international databases; Biographical surveys; Purchase of articles via Bireme/SCAD; Guidance for research in national and international databases; Guidance, search and location of information and bibliographical materials in local databases (physical collection); Bibliographical guidance (assistance for the preparation of references and citations); Selective dissemination of information: sending of monthly summaries of the main periodicals in the area to the library members.

Didactic and Institutional Activity Support: Graphic production. Class set-up; Burning CDs and DVDs; Video editing; Scanner images, slides and negatives; Image treatment; Creation of logo, banners, folder and images; Specialized technical support for Teleorthopedics; Technical IT user support.

We have 2 librarians available to assist our students in whatever they need for the development and standardization of theses and dissertations.

We also have a library located at the USP Medical School that is integrated with the contents of the Digital Intellectual Production Library and the Virtual Health Sciences Education Library. It has tables for collaborative work among students, with access to Led TVs for projections, and a high-performance luminosity multimedia projector. There are 40 Tablets and 10 Ultrabooks on loan to students for use within the library, internet access via Wi-Fi (high-performance routers) with usage time control (similar to Telecenters) and via cable (at the interactive tables or download stands), 4 60-inch interactive Led TVs (Smart TV type) with mobile support and with Wi-Fi or Bluetooth data reception features, 50 individual headsets with Wi-Fi transmitters on loan (similar to the simultaneous translation system) and a user support center with 1 black and white laser printer, 1 table scanner, 1 camera and one color laser printer.

It has access to several databases, such as Dedalus, SIBi (Integrated Library System of the University of São Paulo), PBi (Integrated Search Portal), BVS (Virtual Health Library), PubMed, in addition to Embase, Scopus, UpToDate, Web of Science and others.

The 2019 overview for the FMUSP Library services and products was:

Collection – 54,612 books, 14,773 theses, 253,546 issues of periodicals, 182 multimedia and 49,917 others. Overall total of the collection: 373,030.

Circulation in the collection – 8,414 loans, 18,506 consultations, E-books: 25,740 accesses and 4,207 downloads.

FMUSP Digital Dissertations and Theses (data from BDTD – Digital Dissertation and Thesis Library): 3,948 theses, 2,611 dissertations, 39 habilitation (“livre-docência”) theses. Overall total: 6,598

The Library team organizes all the information of the Intellectual Production Observatory of the FMUSP-HC System, which aims to bring together and give visibility to joint works of national and international relevance, with automated access to the most relevant scientific production of the HCFMUSP Institutes, the FMUSP, the University Hospital – HU, the Tropical Medicine Institute – IMT and the Medical Investigation Laboratories – LIMs.

The FMUSP Library also organizes several courses and events open to undergraduate and graduate students, which are posted on the Medical School website.

ADMINISTRATION:

In addition to the structure dedicated directly to graduate studies, the Program has access to the services and support structure of the HCFMUSP Institute of Orthopedics and Traumatology.

We highlight the following complementary administrative and technical support services:

  • IOT-HCFMUSP Administration Center (Executive Board, Executive Board Technical Advisory, Nursing Division Board, Physical Medicine Board, Board Council Secretariat, Clinical Body Secretariat, Physical Therapy Service Secretariat, Social Medical Services Secretariat, Institutional Communications Center, Administrative Services, Human Resources Secretariat, Hospital Infection Control Center – CCIH, Hospital Sentinel – ANVISA-MS, Permanent Education Center and meeting rooms)
  • Planning and Management Unit (Medical School Foundation Management Center)
  • Secretariat of the Orthopedic Foundation – FO and the Godoy-Moreira Study Center – CEGOM
  • Information Technology Center (program development and IOT NET network systems support)
  • General Patient Records
  • Scientific Documentation Center (medical archives)
  • Reprography
  • Medical Resident Living Area
  • Nutrition and Dietetic Service (Kitchen and Dining Rooms) associated with the Experimental Kitchen
  • Conservation and Repair Service
  • Supply Service
  • Messenger Center
  • Protocol

Also noteworthy is the academic structure of meeting rooms and classrooms at the disposal of the advisors and students:

  • FMUSP Department of Orthopedics and Traumatology (Secretariat of Full Professors, Undergraduate and stricto sensu and lato sensu Graduate Secretariat)
  • Scientific Board and Secretariat of the Scientific Commission of IOT-HCFMUSP and DOT-FMUSP
  • Library Scientific and Academic Documentation Service – SBDCD
  • Teleorthopedics Room (distance learning, video and teleconferencing)
  • Pediatric Orthopedics and Specialty Orthopedics Room
  • Specialty Group Room (five separate rooms)
  • General Orthopedics and Traumatology, Hand and Microsurgery Room
  • Amphitheaters
  • Auditoriums and classrooms (5)
  • Event Areas (2)