{"id":550,"date":"2020-05-01T22:13:31","date_gmt":"2020-05-02T01:13:31","guid":{"rendered":"http:\/\/www.musculoesqueleticousp.com.br\/?page_id=550"},"modified":"2024-06-21T10:37:26","modified_gmt":"2024-06-21T13:37:26","slug":"alexandre-fogaca-cristante","status":"publish","type":"page","link":"https:\/\/www.musculoesqueleticousp.com.br\/es\/pesquisas\/orientadores\/alexandre-fogaca-cristante\/","title":{"rendered":"Alexandre Foga\u00e7a Cristante"},"content":{"rendered":"

\"\"<\/strong>T\u00edtulo:<\/strong> Professor Titular
\nE-mail: <\/strong>aacristante@gmail.com<\/a>
\nLattes: <\/strong>http:\/\/lattes.cnpq.br\/7705881205786732<\/a>
\nOrcid<\/strong>: ID 0000-0002-7797-5274 – \u00a0\u00a0https:\/\/orcid.org\/0000-0002-7797-5274<\/a>
\nScopus<\/strong>: ID \u00a06508026949 – https:\/\/www.scopus.com\/authid\/detail.uri?authorId=6508026949<\/a>
\nGoogle Scholar<\/strong>: ID Gm8toh4AAAAJ \u00a0– \u00a0https:\/\/scholar.google.com.br\/citations?hl=pt-BR&user=Gm8toh4AAAAJ<\/a>
\nResearch ID<\/strong>: K-1841-2016 – https:\/\/publons.com\/researcher\/2243275\/alexandre-f-cristante\/<\/a><\/p>\n

 <\/p>\n

L\u00ednea de investigaciones:<\/strong><\/h2>\n

Principales:<\/strong> Traumatismo raquimedular; Deformidades de columna; T\u00e9cnicas m\u00ednimamente invasivas para cirug\u00eda de columna vertebral<\/p>\n

Resumen<\/h2>\n

Letran <\/strong>–\u00a0laboratorio especializado para las investigaciones experimentales en el \u00e1rea de reparaci\u00f3n y reconstrucci\u00f3n nerviosa. Implant\u00f3, estandariz\u00f3 y valid\u00f3 el modelo experimental de lesi\u00f3n de m\u00e9dula espinal en ratones Wistar. Dispone de un equipamiento computadorizado de impacto por ca\u00edda de peso (New York Impactor) para la producci\u00f3n de contusiones medulares de forma estandarizada y reproductible que fue desarrollado por la New York University \u2013 EE.UU., y adoptado por el \u201cMulticenter Animal Spinal Cord Injury Study \u2013 MASCIS\u201d, coordinado por el Prof. Wise Young de la Rutgers University, EE.UU. Desarrolla, en el momento, nuevas t\u00e9cnicas terap\u00e9uticas con el empleo de c\u00e9lulas madre, de factores de crecimiento y de ingenier\u00eda de tejidos. Se constituye en una de las principales herramientas de investigaci\u00f3n avanzada del CENATRA.\u00a0Estamos desarrollando nuevas formas de evaluaci\u00f3n de recuperaci\u00f3n motora de los ratones, desarrollando aparatos para rehabilitaci\u00f3n de ratones para evaluar la importancia de \u00e9sta en la recuperaci\u00f3n de la lesi\u00f3n medular; y estamos firmando alianzas con otros laboratorios para mejora continua de nuestras investigaciones.<\/p>\n

C<\/strong>enatra <\/strong>–\u00a0Centro de Referencia para Atenci\u00f3n Especializada Integral al Traumatismo Raquimedular.\u00a0L\u00ednea de actuaci\u00f3n: Programa de car\u00e1cter nuclear, multic\u00e9ntrico, interinstitucional, multidisciplinario y multiprofesional para asistencia m\u00e9dica, terciaria y cuaternaria, y param\u00e9dica a los pacientes v\u00edctimas de traumatismo raquimedular. Mantiene actividades de ense\u00f1anza de grado y de postgrado lato sensu y stricto sensu, de investigaci\u00f3n cl\u00ednica y tecnol\u00f3gica, b\u00e1sica y aplicada, de formaci\u00f3n tecnol\u00f3gica y de recursos humanos, de orientaci\u00f3n y de difusi\u00f3n de conocimientos para la comunidad. Prev\u00e9, adem\u00e1s, actividades pre (campa\u00f1as de prevenci\u00f3n, etc.) y posthospitalarias (programas de autocuidados y de formaci\u00f3n de cuidadores informales, de reinclusi\u00f3n socio-econ\u00f3mica, etc.)<\/p>\n

Art\u00edculos relevantes:<\/h2>\n
    \n
  1. Paschon V, Correia FF, Morena BC, da Silva VA, Dos Santos GB, da Silva MCC, Cristante AF, Willerth SM, Perrin FE, Kihara AH. CRISPR, Prime Editing, Optogenetics, and DREADDs: New Therapeutic Approaches Provided by Emerging Technologies in the Treatment of Spinal Cord Injury. Mol Neurobiol. 2020 Apr;57(4):2085-2100.<\/li>\n
  2. Paschon V, Morena BC, Correia FF, Beltrame GR, Dos Santos GB, Cristante AF, Kihara AH. VDAC1 is essential for neurite maintenance and the inhibition of its oligomerization protects spinal cord from demyelination and facilitates locomotor function recovery after spinal cord injury. Sci Rep. 2019 Oct 1;9(1):14063.<\/li>\n
  3. Petersen PA, Marcon RM, Letaif OB, Mello Santos MA, Oliveira RG, Passos de Barros Filho TE, Cristante AF. Does Kyphectomy Improve the Quality of Life of Patients With \u00a0yelomeningocele? Clin Orthop Relat Res. 2020 Jan;478(1):104-111.<\/li>\n
  4. Barros AGC, Cristante AF, Santos GBD, Natalino RJM, Ferreira RJR, Barros-Filho TEP. Evaluation of the effects of erythropoietin and interleukin-6 in rats submitted to acute spinal cord injury. Clinics (Sao Paulo). 2019;74:e674.<\/li>\n
  5. Huang H, Sun T, Chen L, Moviglia G, Chernykh E, von Wild K, Deda H, Kang KS, Kumar A, Jeon SR, Zhang S, Brunelli G, Bohbot A, Soler MD, Li J, Cristante AF, Xi H, Onose G, Kern H, Carraro U, Saberi H, Sharma HS, Sharma A, He X, Muresanu D, Feng S, Otom A, Wang D, Iwatsu K, Lu J, Al-Zoubi A. Consensus of clinical neurorestorative progress in patients with complete chronic spinal cord injury. Cell Transplant. 2014;23 Suppl 1:S5-17.<\/li>\n<\/ol>\n

     <\/p>\n

    PROJETOS ORIENTADOR\/ LINHA<\/strong><\/h2>\n

    Linha 1. MODELOS PARA AN\u00c1LISE DE LES\u00d5ES DO SISTEMA NERVOSO
    \n<\/strong>PROJETO ALEXANDRE FOGA\u00c7A<\/strong>: MODELOS EXPERIMENTAIS DE TRAUMATISMOS DA MEDULA ESPINAL
    \nLinha 3. DIST\u00daRBIOS DEGENERATIVOS, INFLAMAT\u00d3RIOS E ESTRUTURAIS DO SISTEMA LOCOMOTOR
    \n<\/strong>PROJETO ALEXANDRE FOGA\u00c7A:<\/strong> ALTERA\u00c7\u00d5ES DEGENERATIVAS DA COLUNA VERTEBRAL
    \nPROJETO ALEXANDRE FOGA\u00c7A:<\/strong> DEFORMIDADE DE COLUNA VERTEBRAL<\/p>","protected":false},"excerpt":{"rendered":"

    T\u00edtulo: Professor Titular E-mail: aacristante@gmail.com Lattes: http:\/\/lattes.cnpq.br\/7705881205786732 Orcid: ID 0000-0002-7797-5274 – \u00a0\u00a0https:\/\/orcid.org\/0000-0002-7797-5274 Scopus: ID \u00a06508026949 – https:\/\/www.scopus.com\/authid\/detail.uri?authorId=6508026949 Google Scholar: ID Gm8toh4AAAAJ \u00a0– \u00a0https:\/\/scholar.google.com.br\/citations?hl=pt-BR&user=Gm8toh4AAAAJ Research ID: K-1841-2016 […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":25,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-550","page","type-page","status-publish","hentry"],"yoast_head":"\nAlexandre Foga\u00e7a Cristante - P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/alexandre-fogaca-cristante\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Alexandre Foga\u00e7a Cristante - 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