{"id":2783,"date":"2024-03-23T11:35:07","date_gmt":"2024-03-23T14:35:07","guid":{"rendered":"https:\/\/www.musculoesqueleticousp.com.br\/?page_id=2783"},"modified":"2024-06-18T16:17:39","modified_gmt":"2024-06-18T19:17:39","slug":"ana-cristina-de-medeiros-ribeiro","status":"publish","type":"page","link":"https:\/\/www.musculoesqueleticousp.com.br\/es\/pesquisas\/orientadores\/ana-cristina-de-medeiros-ribeiro\/","title":{"rendered":"Ana Cristina de Medeiros Ribeiro"},"content":{"rendered":"

\"\"<\/strong><\/p>\n

T\u00edtulo:<\/strong> livre-docente
\nE-mail: <\/strong>ana.medeiros@hc.fm.usp.br
\nLattes: <\/strong>2458188374782290http:\/\/lattes.cnpq.br\/2458188374782290<\/a>
\nOrcid<\/strong>:\u00a0 0000-0001-7168-590\u00a0\u00a0 \u00a0<\/a>https:\/\/orcid.org\/0000-0001-7168-5906<\/a>
\nScopus<\/strong>: 57221695832 https:\/\/www.scopus.com\/authid\/detail.uri?authorId=57221695832<\/a>
\nGoogle Scholar<\/strong>: https:\/\/scholar.google.com.br\/citations?user=7zL6V4kAAAAJ&hl=pt-BR<\/a>
\nResearch ID<\/strong>: GRY-0453-2022\u00a0https:\/\/www.webofscience.com\/wos\/author\/record\/33320671<\/a><\/p>\n

 <\/p>\n

 <\/p>\n

L\u00ednea de investigaci\u00f3n<\/strong><\/h2>\n

Efectividad y complicaciones del tratamiento inmunosupresor en pacientes con artritis inflamatoria.<\/p>\n

Resumen<\/strong><\/h2>\n

La l\u00ednea de investigaci\u00f3n eval\u00faa la efectividad, predictores y complicaciones de los tratamientos en pacientes reumatol\u00f3gicos, principalmente con artritis inflamatoria, como artritis reumatoide, espondilitis anquilosante y artritis psori\u00e1sica. El uso de agentes inmunobiol\u00f3gicos, inmunosupresores convencionales y terapia con corticosteroides se eval\u00faa mediante el an\u00e1lisis de cohortes longitudinales desde el inicio hasta el tratamiento, con \u00e9nfasis en la supervivencia de los f\u00e1rmacos, los mecanismos de acci\u00f3n, los predictores de respuesta y las estrategias de retirada de medicamentos. Adem\u00e1s, se eval\u00faan las complicaciones del tratamiento, como reacciones a la infusi\u00f3n e infecciones, y se estudian estrategias para reducir el riesgo infeccioso, como la vacunaci\u00f3n y otras estrategias preventivas. La l\u00ednea de investigaci\u00f3n eval\u00faa la seguridad, inmunogenicidad y eficacia de vacunas de diferentes plataformas, as\u00ed como estrategias para optimizar la respuesta vacunal, como el impacto de interrumpir temporalmente los inmunosupresores tras la vacunaci\u00f3n.<\/p>\n

Publicaciones principales<\/strong>: <\/strong><\/h2>\n
    \n
  1. Medeiros-Ribeiro AC<\/strong>, Aikawa NE, Saad CGS, Yuki EFN, Pedrosa T, Fusco SRG, Rojo PT, Pereira RMR, Shinjo SK, Andrade DCO, Sampaio-Barros PD, Ribeiro CT, Deveza GBH, Martins VAO, Silva CA, Lopes MH, Duarte AJS, Antonangelo L, Sabino EC, Kallas EG, Pasoto SG, Bonfa E. Immunogenicity and safety of the CoronaVac inactivated vaccine in patients with autoimmune rheumatic diseases: a phase 4 trial. Nat Med. 2021;27(10):1744-1751. (Fator de Impacto 87.241).<\/strong><\/li>\n
  2. Aikawa NE, Kupa LVK, Pasoto SG, Medeiros-Ribeiro AC,<\/strong> Yuki EFN, Saad CGS, Pedrosa T, Fuller R, Shinjo SK, Sampaio-Barros PD, Andrade DCO, Pereira RMR, Seguro LPC, Valim JML, Waridel F, Sartori AMC, Duarte AJS, Antonangelo L, Sabino EC, Menezes PR, Kallas EG, Silva CA, Bonfa E. Immunogenicity and safety of two doses of the CoronaVac SARS-CoV-2 vaccine in SARS-CoV-2 seropositive and seronegative patients with autoimmune rheumatic diseases in Brazil: a subgroup analysis of a phase 4 prospective study. Lancet Rheumatol. 2022;4(2):e113-e124. (Fator de Impacto 35.482).<\/strong><\/li>\n
  3. Medeiros-Ribeiro AC,<\/strong> Bonfiglioli KR, Domiciano DS, Shimabuco AY, da Silva HC, Saad, CGS , Yuki EFN, Pasoto SG, Araujo CSR, Nakai TL,\u00a0 Silva CA, Pedrosa T,\u00a0 Kupa LVK, Silva MSR, Balbi\u00a0 GGM, Kallas EG, Aikawa NE, Bonfa E. Distinct Impact df DMARD Combination and Monotherapy in Immunogenicity of an Inactivated Sars-Cov-2 Vaccine in Rheumatoid Arthritis. Annals of the Rheumatic Diseases. 2022; 81; 710-719.(Fator de Impacto: 27.993).<\/strong><\/li>\n
  4. Araujo CSR, Medeiros-Ribeiro AC,<\/strong> Saad CGS, Bonfiglioli KR, Domiciano DS, Shimabuco AY, Silva MSR, Yuki EFN, Pasoto SG, Pedrosa T, Kupa LVK, Zou G, Pereira RMR, Silva CA, Aikawa NE, Bonfa E. Two-week methotrexate discontinuation in patients with rheumatoid arthritis vaccinated with inactivated SARS-CoV-2 vaccine: a randomised clinical trial. Ann Rheum Dis. 2022 Jun;81(6):889-897. (Fator de Impacto: 27.993).<\/strong><\/li>\n
  5. \u00a0Ribeiro ACM, <\/strong>Guedes LKN, Moraes JCB, Saad CGS, Aikawa NE, Calich ALG, Franca ILA, Carvalho JF, Sampaio-Barros PD, Gon\u00e7alves CR, Borba EF, Timenetsky MCST, <\/a>\u00a0Precioso AR, Duarte A, Bonf\u00e1 E, Laurindo IMM. Reduced seroprotection after pandemic H1N1 in\ufb02uenza adjuvant-free vaccination in patients with rheumatoid arthritis: implications for clinical practice. 2011. Annals of the Rheumatic Diseases; 70; 2144-2147. (Fator de Impacto: 27.993).<\/strong><\/li>\n<\/ol>\n

     <\/p>\n

    PROJETOS ORIENTADOR\/ LINHA<\/strong><\/h2>\n

    Linha 6. SISTEMA IMUNE E AUTOIMUNE
    \n<\/strong>PROJETO ANA CRISTINA:<\/strong> ESTUDOS DE IMUNOGENICIDADE E EFETIVIDADE DA VACINA\u00c7\u00c3O C ONTRA SARS-COV-2 EM PACIENTES COM ARTROPATIAS INFLAMAT\u00d3RIAS.
    \nPROJETO ANA CRISTINA: <\/strong>ESTUDOS DE SEGURAN\u00c7A, EFETIVIDADE E PREDITORES DE RESPOSTA A AGENTES IMUNOBIOL\u00d3GICOS EM PACIENTES COM ARTROPATIAS\u00a0 INFLAMAT\u00d3RIAS.<\/p>","protected":false},"excerpt":{"rendered":"

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