The line of research of the laboratory is \u201cTissue and molecular aspects of the structure and function of extracellular matrix proteins in inflammatory and fibrotic processes\u201d, and its objective is to investigate the tissue and molecular aspects of the structure and function of extracellular matrix proteins with emphasis on the different isoforms of collagen. It is known that collagen, in addition to being responsible for tissue structure, performs functions of cell adhesion, proliferation and migration and that together with the glycoproteins of the cell membrane can promote cellular signaling and immunogenicity. Uncontrolled gene expression synthesis from post-transcriptional changes or changes in essential transcription factors leads to defects in the differentiation and proliferation of cells that culminate in the activation of inflammatory and fibrotic processes present in degenerative autoimmune and osteoarticular diseases. The proposal of the laboratory is to evaluate the inflammatory and osteoarticular process control mechanisms that culminate in the activation of the inflammatory process and cell proliferation and differentiation \u201cin vitro\u201d and \u201cin vivo\u201d in animals and humans, focusing on the applicability of the knowledge generated to future therapeutic and diagnostic tools.<\/p>\n
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The line of research of the laboratory is \u201cTissue and molecular aspects of the structure and function of extracellular matrix proteins in inflammatory and fibrotic processes\u201d, […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":466,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-513","page","type-page","status-publish","hentry"],"yoast_head":"\n