{"id":2014,"date":"2022-07-25T09:12:08","date_gmt":"2022-07-25T12:12:08","guid":{"rendered":"https:\/\/www.musculoesqueleticousp.com.br\/?page_id=2014"},"modified":"2024-08-02T09:21:07","modified_gmt":"2024-08-02T12:21:07","slug":"carolina-nicoletti","status":"publish","type":"page","link":"https:\/\/www.musculoesqueleticousp.com.br\/en\/pesquisas\/orientadores\/carolina-nicoletti\/","title":{"rendered":"Carolina Nicoletti"},"content":{"rendered":"

\"\"<\/strong><\/p>\n

Titula\u00e7\u00e3o: <\/strong>P\u00f3s-Doutorado
\nE-mail:\u00a0<\/strong>carolina.nicoletti.ferreira@usp.br
\nLattes:\u00a0<\/strong>\u00a0http:\/\/lattes.cnpq.br\/3155405354051140<\/a>
\nOrcid: <\/strong>ID 0000-0002-4610-5786 – <\/strong>https:\/\/orcid.org\/0000-0002-4610-5786 <\/strong><\/a>
\nScopus<\/strong>:\u00a0ID 7004016534 – https:\/\/www.scopus.com\/authid\/detail.uri?authorId=7004016534 <\/a>
\nGoogle Scholar<\/strong>: cRz88dsAAAAJ –\u00a0 https:\/\/scholar.google.com.br\/citations?hl=pt-BR&user=<\/a> cRz88dsAAAAJ
\nResearch ID:<\/strong> J-2948-2015 – https:\/\/publons.com\/wos-op\/researcher\/2379552\/carolina-f-nicoletti<\/a><\/p>\n

 <\/p>\n

Linha de pesquisa <\/strong><\/h2>\n

Epigen\u00e9tica Nutricional nas Doen\u00e7as Reum\u00e1ticas<\/p>\n

Summary<\/strong><\/h2>\n

The research line “Nutritional Epigenetics in Rheumatic Diseases” aims to elucidate whether there is an epigenetic signature related to the phenotype of lupus and obesity. More specifically, it investigates the role of obesity in the DNA methylation pattern in this disease and whether this profile is associated with the manifestations of the disease, as well as whether nutritional treatments, primarily with methyl group donor nutrients, can epigenetically modulate the genome. I am currently conducting in vivo, in vitro, and human studies, which characterizes a translational approach. Collectively, this ambitious and comprehensive research line will provide new insights into the complex relationship between lupus and obesity, as advances in precision medicine\/nutrition will be important for the treatment of patients with lupus, especially those with obesity.<\/p>\n

Principais publica\u00e7\u00f5es<\/strong><\/h2>\n
    \n
  1. Nicoletti CF, Cortes-Oliveira C, Noronha NY, Pinhel MAS, Dantas WS, J\u00e1come A, Marchini JS, Gualano B, Crujeiras AB, Nonino CB. DNA methylation pattern changes following a short-term hypocaloric diet in women with obesity. Eur J Clin Nutr. 2020;74(9):1345-1353. doi: 10.1038\/s41430-020-0660-1.<\/li>\n
  2. Nicoletti CF, Pinhel MAS, Noronha NY, de Oliveira BA, Salgado Junior W, J\u00e1come A, Diaz-Lagares A, Casanueva F, Crujeiras AB, Nonino CB. Altered pathways in methylome and transcriptome longitudinal analysis of normal weight and bariatric surgery women. Sci Rep. 2020;10(1): 6515. doi:10.1038\/s41598-020-60814-9.<\/li>\n
  3. Nicoletti CF, Pinhel MAS, Diaz-Lagares A, Casanueva FF, J\u00e1come A, Pinhanelli VC, de Oliveira BAP, Crujeiras AB, Nonino CB. DNA methylation screening after roux-en Y gastric bypass reveals the epigenetic signature stems from genes related to the surgery per se. BMC Med Genomics. 2019 May 27;12(1):72. doi: 10.1186\/s12920-019-0522-7.<\/li>\n
  4. Fraszczyk E, Luijten M, Spijkerman AMW, Snieder H, Wackers PFK, Bloks VW, Nicoletti CF, Nonino CB, Crujeiras AB, Buurman WA, Greve JW, Rensen SS, Wolffenbuttel BHR, van Vliet-Ostaptchouk JV. The effects of bariatric surgery on clinical profile, DNA methylation, and ageing in severely obese patients. Clin Epigenetics. 2020;12(1):14. doi: 10.1186\/s13148-019-0790-2.<\/li>\n
  5. Nicoletti CF, Nonino CB, de Oliveira BA, Pinhel MA, Mansego ML, Milagro FI,Zulet MA, Martinez JA. DNA Methylation and Hydroxymethylation Levels in Relationto Two Weight Loss Strategies: Energy-Restricted Diet or Bariatric Surgery. Obes Surg. 2016;26(3):603-11. doi: 10.1007\/s11695-015-1802-8.<\/li>\n<\/ol>\n

     <\/p>\n

    PROJETOS ORIENTADOR\/ LINHA<\/strong><\/h2>\n

    Linha 7. EFEITOS DO EXERC\u00cdCIO F\u00cdSICO, NUTRI\u00c7\u00c3O E GEN\u00c9TICA NA SA\u00daDE E NO DESEMPENHO F\u00cdSICO
    \n<\/strong>PROJETO CAROLINA NICOLETTI:<\/strong> ASSINATURAS EPIGEN\u00c9TICAS NO TECIDO ADIPOSO
    \nPROJETO CAROLINA NICOLETTI<\/strong>: GEN\u00d4MICA NUTRICIONAL NAS DOEN\u00c7AS CR\u00d4NICAS E\/OU REUM\u00c1TICAS<\/p>","protected":false},"excerpt":{"rendered":"

    Titula\u00e7\u00e3o: P\u00f3s-Doutorado E-mail:\u00a0carolina.nicoletti.ferreira@usp.br Lattes:\u00a0\u00a0http:\/\/lattes.cnpq.br\/3155405354051140 Orcid: ID 0000-0002-4610-5786 – https:\/\/orcid.org\/0000-0002-4610-5786 Scopus:\u00a0ID 7004016534 – https:\/\/www.scopus.com\/authid\/detail.uri?authorId=7004016534 Google Scholar: cRz88dsAAAAJ –\u00a0 https:\/\/scholar.google.com.br\/citations?hl=pt-BR&user= cRz88dsAAAAJ Research ID: J-2948-2015 – https:\/\/publons.com\/wos-op\/researcher\/2379552\/carolina-f-nicoletti   Linha […]<\/p>\n","protected":false},"author":3,"featured_media":0,"parent":25,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2014","page","type-page","status-publish","hentry"],"yoast_head":"\nCarolina Nicoletti - P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Carolina Nicoletti - P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico\" \/>\n<meta property=\"og:description\" content=\"Titula\u00e7\u00e3o: P\u00f3s-Doutorado E-mail:\u00a0carolina.nicoletti.ferreira@usp.br Lattes:\u00a0\u00a0http:\/\/lattes.cnpq.br\/3155405354051140 Orcid: ID 0000-0002-4610-5786 – https:\/\/orcid.org\/0000-0002-4610-5786 Scopus:\u00a0ID 7004016534 – https:\/\/www.scopus.com\/authid\/detail.uri?authorId=7004016534 Google Scholar: cRz88dsAAAAJ –\u00a0 https:\/\/scholar.google.com.br\/citations?hl=pt-BR&user= cRz88dsAAAAJ Research ID: J-2948-2015 – https:\/\/publons.com\/wos-op\/researcher\/2379552\/carolina-f-nicoletti   Linha […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/\" \/>\n<meta property=\"og:site_name\" content=\"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico\" \/>\n<meta property=\"article:modified_time\" content=\"2024-08-02T12:21:07+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2022\/07\/FOTO_CAROLINA-295x300.jpg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"8 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/\",\"url\":\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/\",\"name\":\"Carolina Nicoletti - P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico\",\"isPartOf\":{\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2022\/07\/FOTO_CAROLINA-295x300.jpg\",\"datePublished\":\"2022-07-25T12:12:08+00:00\",\"dateModified\":\"2024-08-02T12:21:07+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#primaryimage\",\"url\":\"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2022\/07\/FOTO_CAROLINA-295x300.jpg\",\"contentUrl\":\"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2022\/07\/FOTO_CAROLINA-295x300.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research\",\"item\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/pesquisas\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Orientadores\",\"item\":\"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Carolina Nicoletti\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/#website\",\"url\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/\",\"name\":\"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico\",\"description\":\"Website do P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico\",\"publisher\":{\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/#organization\",\"name\":\"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico\",\"url\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2020\/04\/logo_pg_cme_v3_h120.png\",\"contentUrl\":\"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2020\/04\/logo_pg_cme_v3_h120.png\",\"width\":481,\"height\":120,\"caption\":\"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico\"},\"image\":{\"@id\":\"https:\/\/www.musculoesqueleticousp.com.br\/en\/#\/schema\/logo\/image\/\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Carolina Nicoletti - P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/","og_locale":"en_US","og_type":"article","og_title":"Carolina Nicoletti - P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico","og_description":"Titula\u00e7\u00e3o: P\u00f3s-Doutorado E-mail:\u00a0carolina.nicoletti.ferreira@usp.br Lattes:\u00a0\u00a0http:\/\/lattes.cnpq.br\/3155405354051140 Orcid: ID 0000-0002-4610-5786 – https:\/\/orcid.org\/0000-0002-4610-5786 Scopus:\u00a0ID 7004016534 – https:\/\/www.scopus.com\/authid\/detail.uri?authorId=7004016534 Google Scholar: cRz88dsAAAAJ –\u00a0 https:\/\/scholar.google.com.br\/citations?hl=pt-BR&user= cRz88dsAAAAJ Research ID: J-2948-2015 – https:\/\/publons.com\/wos-op\/researcher\/2379552\/carolina-f-nicoletti   Linha […]","og_url":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/","og_site_name":"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico","article_modified_time":"2024-08-02T12:21:07+00:00","og_image":[{"url":"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2022\/07\/FOTO_CAROLINA-295x300.jpg","type":"","width":"","height":""}],"twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"8 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/","url":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/","name":"Carolina Nicoletti - P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico","isPartOf":{"@id":"https:\/\/www.musculoesqueleticousp.com.br\/en\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#primaryimage"},"image":{"@id":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#primaryimage"},"thumbnailUrl":"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2022\/07\/FOTO_CAROLINA-295x300.jpg","datePublished":"2022-07-25T12:12:08+00:00","dateModified":"2024-08-02T12:21:07+00:00","breadcrumb":{"@id":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#primaryimage","url":"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2022\/07\/FOTO_CAROLINA-295x300.jpg","contentUrl":"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2022\/07\/FOTO_CAROLINA-295x300.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/carolina-nicoletti\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/www.musculoesqueleticousp.com.br\/en\/"},{"@type":"ListItem","position":2,"name":"Research","item":"https:\/\/www.musculoesqueleticousp.com.br\/en\/pesquisas\/"},{"@type":"ListItem","position":3,"name":"Orientadores","item":"https:\/\/www.musculoesqueleticousp.com.br\/pesquisas\/orientadores\/"},{"@type":"ListItem","position":4,"name":"Carolina Nicoletti"}]},{"@type":"WebSite","@id":"https:\/\/www.musculoesqueleticousp.com.br\/en\/#website","url":"https:\/\/www.musculoesqueleticousp.com.br\/en\/","name":"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico","description":"Website do P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico","publisher":{"@id":"https:\/\/www.musculoesqueleticousp.com.br\/en\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.musculoesqueleticousp.com.br\/en\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/www.musculoesqueleticousp.com.br\/en\/#organization","name":"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico","url":"https:\/\/www.musculoesqueleticousp.com.br\/en\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.musculoesqueleticousp.com.br\/en\/#\/schema\/logo\/image\/","url":"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2020\/04\/logo_pg_cme_v3_h120.png","contentUrl":"https:\/\/www.musculoesqueleticousp.com.br\/wp-content\/uploads\/2020\/04\/logo_pg_cme_v3_h120.png","width":481,"height":120,"caption":"P\u00f3s-Gradua\u00e7\u00e3o em Ci\u00eancias do Sistema Musculoesquel\u00e9tico"},"image":{"@id":"https:\/\/www.musculoesqueleticousp.com.br\/en\/#\/schema\/logo\/image\/"}}]}},"_links":{"self":[{"href":"https:\/\/www.musculoesqueleticousp.com.br\/en\/wp-json\/wp\/v2\/pages\/2014","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.musculoesqueleticousp.com.br\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.musculoesqueleticousp.com.br\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.musculoesqueleticousp.com.br\/en\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.musculoesqueleticousp.com.br\/en\/wp-json\/wp\/v2\/comments?post=2014"}],"version-history":[{"count":9,"href":"https:\/\/www.musculoesqueleticousp.com.br\/en\/wp-json\/wp\/v2\/pages\/2014\/revisions"}],"predecessor-version":[{"id":3063,"href":"https:\/\/www.musculoesqueleticousp.com.br\/en\/wp-json\/wp\/v2\/pages\/2014\/revisions\/3063"}],"up":[{"embeddable":true,"href":"https:\/\/www.musculoesqueleticousp.com.br\/en\/wp-json\/wp\/v2\/pages\/25"}],"wp:attachment":[{"href":"https:\/\/www.musculoesqueleticousp.com.br\/en\/wp-json\/wp\/v2\/media?parent=2014"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}